Tuesday, April 30, 2013

EE's 4G LTE comes to 12 new markets

EE

Total EE 4G c?ities reaches 62, carrier says

EE, the UK's first and currently only 4G LTE network operator, sends word that it's just flipped the switch on LTE in another twelve towns across the country.

From today, EE's 4G services are available in Aylesbury, Berkhamsted, Billericay, Blackpool, Brentwood, Dewsbury, Huddersfield, Lytham St Annes, Marlow, Pontefract, Thame and Windsor. The list of new markets shows LTE spreading further into rural areas, and EE says its 4G network now covers more than 50 percent of the UK population. By the end of June, the operator says it'll have reached a further 18 markets, and aims to bring its coverage up to 70 percent of the population by the end of the year.

EE is sure to face more competition in the coming months, as rival networks launch their own 4G offerings based on the 800MHz and 2600MHz spectrum auctioned off earlier in the year. Vodafone, O2 and Three are expected to launch LTE networks of their own later this year, in some cases possibly as early as this summer.

Press release is after the break.

read more

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/e6CP3OCG9vU/story01.htm

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Monday, April 29, 2013

Beyond The Box Launches A TweetDeck For Sports To Bring Realtime News And Analysis To Your iPad

Screen shot 2013-04-28 at 12.55.08 AMLike many avid sports fans, Shailo Rao, Sagar Savant and Vam Makam are well-familiar with how frustrating it can be to find quality, relevant sports content -- especially on Twitter and other social media. Rao tells me over coffee that, as a PhD student at Stanford, he spent years trying to create and maintain a single realtime feed of content he actually cared about. Because no company or publication was addressing this at the time, he was forced to manually curate a huge roster of RSS feeds from his favorite websites and Twitter accounts.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/g52_tmII1EM/

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Dealing with Home Remodeling Careers? Go through These ...

Home improvement jobs can feel just like an interest or an endless fixation. Additionally, it may add value to your residence. This short article may help you make great choices when it comes to planning your brand new assignments and ensuring that vital faults don?t take place.

Granite floor tile is an affordable option to a granite slab if you would like cut costs.Granite slab can cost a pretty dime. It is possible to cover exactly the same area with high quality granite ceramic tiles that only cost you a couple of 100 $ $ $ $ and will also appear just like fantastic. You will also save a lot of money and you can place that into one more venture.

A reliable drill is a crucial resource for just about any home improvement project. A good drill can provide you with a lot of overall flexibility when setting up screws.

Earthenware tiles can dull with time. A remedy of vinegar and h2o will securely thoroughly clean most floors.Fill up a bucket with the answer and initiate mopping your surfaces. The perfect solution reduces grime and dirt leaving your ground again.

Granite ceramic tile is undoubtedly an affordable substitute for a granite slab if you would like spend less.A granite kitchen counter that is made of a slab is going to amount to from the hundreds. You just might protect the same place with high quality granite floor tiles for less funds and this will look equally as fantastic. You will also reduce your cost you stored and use it to another one undertaking if you wish.

If a lock has issues, you should know that one could either substitute the tube or perhaps the total assemblage. The cylinder will be the secure position always. When you don?t possess an essential and you require your fasten being transformed to be much more secure, you are able to alter the cylinder and never have to change complete fasten.

Don?t forget about that patching and/or restoring destroyed regions you could possibly come across.

The wise way to keep your front yard servicing regimen is maintaining it away from particles.

A new family room or den is a superb options for improvements. This will raise the convenience of your residence much more pleasant and also add benefit of your residence.For you to do this task once you have the amount of money to spend on home improvement projects.

Disconnect and nice and clean your overall dryer garden hose. Minimize the hose length down to just a couple of ft in size. You will need additional span to clean, although.

Put an uncommon add-on to your home having a distinctive add-on. A wines cellar or catalogue packed with shelves are two excellent locations to start.This may undoubtedly impress friends and possess an elegant place to reside.

It may be effort to perform changes, nevertheless it pays off in the end. Regardless of level of skill, you can discover the different aspects of redecorating. These tips were built to help those of all levels locate their way into it.

Should you wish for added points about building contractors Glasgow look at Arlena Y. Piefer?s site there?s a lot of details not detailed in this post, visit Author?s web blog to locate more.

Source: http://www.articlessquad.com/dealing-with-home-remodeling-careers-go-through-these-pointers-initially-3/?utm_source=rss&utm_medium=rss&utm_campaign=dealing-with-home-remodeling-careers-go-through-these-pointers-initially-3

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Mobile App Ratings: Teens Review Their Favorite Social Apps From Instagram To GifBoom

This article was written by teen reporters from The Mash, a weekly publication distributed to Chicagoland high schools.

By Ashley Black, St. Charles East high school, and Mikhaela Padilla, Whitney Young high school

The time of simple communication is dwindling toward extinction. Think about it: When?s the last time you called a friend from a landline phone and talked for hours? Year after year, study after study, it?s shown that teens favor communicating through social networks such as Facebook and Twitter.

But now, there?s a new crop of social networking applications that are readily available to teens (aka free)?and there?s something for everyone. Want to show off a vacation photo? Instagram is your best bet. Interested in documenting your life, one check-in at a time? Path can help you with that. Or maybe you just want to send a silly selfie to your best friends? Check out Snapchat.

We rounded up some of the most popular communication apps, tried them out for ourselves and gave them report cards.

Instagram

Instagram allows its users to play professional photographer with filters, a cropping tool and focus options. Plus, you can see what your friends (and celebs) are up to through live updates.
Unlike Facebook and Twitter, Instagram is a photo-only app that banks on creativity. ?People love it because it shows a little bit of your personality and your life,? said Brianna Booth, a freshman at Barrington.

Since Instagram?s launch in 2010, heaps of knockoff apps have debuted. Still, most lack the massive following that Instagram has built.

Instagram did come under fire late last year after changing its terms of service. Users worried that the app could sell their works of art. Instagram cleared that up: You own your photos, but Instagram can share your user data with its parent company, Facebook.

Grade: A
Top marks for: user-friendly tools, creativity and cult-like following
Could improve: confusing service terms

GifBoom

In a nutshell, GifBoom is a moving Instagram. The app makes it easy to create and share your very own gifs (aka animated photographs, like the ones on whatshouldwecallme.tumblr.com). Unlike Tumblr, GifBoom only allows its users to share gifs?no still photos allowed.

One major complaint? It?s not super user-friendly at first. ?It was hard to navigate for the first week,? said Gina Paletta, a freshman at St. Charles East. ?I had no idea what I was doing and it took time to figure out.?

Once you get the hang of it, GifBoom is a unique app to have. If you?ve ever wished your Instagram photos could move, this app is for you.

Grade: B+
Top marks for: growing user base and clean design
Could improve: ease of use and tools

Pheed

If Facebook, Twitter, Instagram and YouTube had a baby (don?t ask us how), it would be Pheed. The easy-to-use, clutter-free app is quickly gaining popularity and followers. You can use Pheed to share texts, photos, videos, audio and live broadcasts.

Some would say the concept is new, but others find it repetitive. ?Facebook is all I need because other apps are basically all just the same,? said Jose Garcia, a junior at Carl Schurz.

But there is something that sets Pheed apart: Users can subscribe to premium channels for a fee (anywhere from $1.99 to $34.99 per month). For example, a singer might broadcast their performance or concert on Pheed and users would have to subscribe?and possibly pay a fee?to view it.

Grade: A-
Top marks for: clutter-free design and ease of use
Could improve: originality and premium fees

Path

If you love the idea of Facebook?s timeline, Path might just be your new favorite app. The new-ish concept allows you to share almost anything: your current location, what you?re listening to, future plans, cute stickers and more. The app also allows you to have conversations with friends (as shown above).

?Facebook and Instagram are easier to use and understand, but Path is a more minute-by-minute timeline of someone?s day,? said Brooke Rinker, a senior at St. Charles East.

One major difference between Facebook and Path is that you can have only 150 friends on Path. It creates a more close-knit feeling for many users, but some find it too restrictive.

Grade: B
Top marks for: live updating and variety
Could improve: sharing restrictions and ease of use

Snapchat

Snapchat is like nothing else on the app market. You take a photo or short video, add text or a doodle and send it to your friends to view for a set amount of time (one to 10 seconds, your choice). Once your friends open the pic, they have to press down on their phone screen to view your photo. After the timer is up, the photo or video disappears forever ? or so we?re told.

?Snapchat allows people to easily share information about their lives on a whole (different) level using photos,? said Willie Stevan, a sophomore at Whitney Young. ?I send about 15 snaps a day and receive, like, 50!?

One downfall? The privacy settings are questionable. A University of Michigan student and hacker, Raj Vir, reported that users secretly can save incoming images. Note to all: Don?t send anything via Snapchat that you wouldn?t want to resurface.

Grade: B+
Top marks for: originality and easy-to-use tools
Could improve: privacy settings

Also on HuffPost:

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Source: http://www.huffingtonpost.com/2013/04/27/mobile-app-ratings-teens-_n_3171661.html

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Sunday, April 28, 2013

Saudi anti-domestic violence campaign sparks media buzz ...

April 28, 2013

?Some things can?t be covered,? reads the slogan of Saudi Arabia?s anti-domestic violence advert.

An image of a burqa-clad woman with a blackened and bloodshot eye, part of a campaign backed by the King Khalid Charitable Foundation, has sparked international media attention.

The campaign will to provide ?legal protection for women and children from abuse in Saudi Arabia,? says behind the campaign.

?The phenomenon of battered women in Saudi Arabia is much greater than apparent,? the foundation wrote in literature for its campaign.

The King Khalid Foundation was established in 2001 by the family of the late King Khalid, who ruled from 1975 in Saudi Arabia until his death in 1982.

Saudis are being encouraged by the campaign to report cases of violence at locations around the Kingdom including Madinah, Najran, Makkah and Riyadh, reported The Huffington Post.

One in every six women is abused verbally, physically or emotionally every day, and 90 percent of the abusers are usually husbands or fathers, said Saudi columnist Samar Fatany, citing studies.

?According to research conducted by the National Family Safety Program, most women are not aware of their rights and some men violate religious teachings and follow aberrant customs and traditions,? Fatany added.

Saudi Arabia?s King Abdullah in recent years has pursued a reformist agenda in terms of women?s rights.

In 2011, women were given the right to vote and run for office in municipal elections in 2015. Earlier this year, members of country?s legislative Shura Council included 30 women.

It was also recently announced that women would be allowed to practice law in a professional environment.

But women in Saudi Arabia still encounter restrictions.

Saudi women are not allowed to drive, take up employment or leave the country without a male guardian?s permission.

In 2011, an SMS system to track women was reported, allowing Saudi authorities to inform male guardians of their whereabouts.

Source: Al Arabiya

Source: http://www.moroccoworldnews.com/2013/04/88827/saudi-anti-domestic-violence-campaign-sparks-media-buzz/

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April is Autism Awareness Month - The Valley News

? It is beneficial for all parents to know the signs of Autism and Autism Spectrum Disorder (ASD) and take actions early if they are concerned about how their child learns, plays, speaks or acts. Autism signs can be seen before age three (3) and last throughout a lifetime and can range from mild to severe.

?About 1 in 100 children has Autism or ASD which can cause significant social, behavioral and communication challenges,? said Lucianna Celotti, Coordinator of the Children with Special Health Care Needs Program of Essex County Public Health.

ASDs are a group of developmental disabilities categorized as Autistic Disorder, Asperger Syndrome and Pervasive Developmental Disorder-Not Otherwise Specified. Children with an ASD may have unusual reactions to sensory input like sounds, smells, tastes, looks or feels; repeat words or phrases; get upset by schedule changes; have difficulty understanding other peoples? feelings; avoid eye contact or prefer to be alone.

?It is important for parents who have concerns about their child?s development to talk to their child?s pediatrician. Children can greatly benefit from early detection and interventions,? said Celotti.

Essex County Public Health (ECPH) offers several programs for children with special health care needs. ?Our Early Intervention Program helps children ages birth through 3 years develop important social, behavioral and communication skills. Our services are provided based on a child?s individual need and are designed to help parents and families nurture their children and encourage skills.?

Learn more about the ECPH Early Intervention Program and other programs for children with special health care needs, visit www.co.essex.ny.us/PublicHealth or call Lucianna Celotti at (518) 873-3500.

Source: http://www.valleynewsadk.com/news/2013/apr/26/april-autism-awareness-month/

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Saturday, April 27, 2013

Gold-Bedecked Skeleton May Have Been Ancient Queen

More than 4,000 years ago, a woman, perhaps an ancient queen, was carefully laid to rest outside of modern-day London, ornamented with beads of gold strung around her neck and a large drinking cup placed at her hip. Archaeologists have just uncovered her grave at a quarry that lies between Windsor Castle and Heathrow airport.

The gold ornaments suggest the woman was important, possibly of the elite and even a princess or queen, the excavators said.

The woman's bones have been degraded by acid in the soil, making radiocarbon dating and DNA analysis impossible. Nonetheless, excavators believe she was at least 35 years old when she died sometime between 2500 B.C. and 2200 B.C., around the era Stonehenge was constructed.

The woman was adorned with a necklace that had tube-shaped beads fashioned out of sheet gold and black disks of lignite, a dark, coal-like material similar to jet. Though her clothing long ago disintegrated, amber buttons and fasteners were scattered across the woman's body in a row, hinting at how she may have been dressed. [8 Grisly Archaeological Discoveries]

The excavation team believes she belonged to the Beaker people, a widespread Neolithic culture that gets its name from the shape of the ceramic pots they left behind. Beaker remains have been found across Europe, but few in Britain have been found with gold ornaments and most contain male skeletons, excavators say.

"It is interesting to think who this woman was within her community," Gareth Chaffey, who has been directing excavations at the site for Wessex Archaeology, said in a statement. "She was probably an important person in her society, perhaps holding some standing which gave her access to prestigious, rare and exotic items. She could have been a leader, a person with power and authority, or possibly part of an elite family ? perhaps a princess or queen."

A good indication of her status might be her jewelry, which was made from materials that were not exactly locally sourced. Analyses showed that the gold likely came from Ireland or southern England and the amber pieces may have originated eastern England or as far away as the Baltic, researchers say.

Wessex Archaeology has been conducting rescue excavations at the quarry in the village of Horton, while the building materials-company CEMEX is extracts sand and gravel. Besides the Beaker burial, archaeologists at the site have found a wide range of ancient remains, from late Ice Age flint tools to post-medieval pig burials. The companies hope the recent finds will end up in a local museum.

Follow Megan Gannon on Twitter and Google+. Follow us @livescience, Facebook & Google+. Original article on LiveScience.com.

Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/gold-bedecked-skeleton-may-ancient-queen-180950994.html

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Friday, April 26, 2013

One Today by Google leads Android Apps of the Week

One Today by GoogleThis week brought us a new app from Google that's actively trying to make the world a better place, one day at a time, one dollar at a time. That app is One Today by Google, and it's the top app of the week. We've also got a new voice activated personal assistant, the ultimate travel-log app, a new way to meet people online, and a way to keep your business and personal lives separate, at least as far as phone numbers are concerned.

Google may be a company hell bent on taking over the entire world, but it's always quite possible that they'll be benevolent and merciful new overlords, ushering us into a new age of peace and prosperity! At least, that's what you might conclude thanks to their new app One Today by Google. Probably the most noble app to be put out by such a massive company, One Today brings a different nonprofit group or project to your attention every single day, and asks that you donate one single dollar to the cause, hopefully sharing that donation with social media and getting larger chunks of change to the people who are trying to make the world better. We're all philanthropists in Google's new world order! But seriously. This is great stuff, and I'm glad to see it.


Also on Android Apps

Instead of celebrating Earth Day once a year, adopt an eco-friendly consciousness. Zinio ?s digital newsstand saves 104 thousand trees per month, and here?s how you can get involved.


Speaking of awesome futuristic scenarios that we've all seen in movies, haven't you always wanted your very own AI assistant and companion? Well? Indigo from Artificial Solutions is a pretty close alternative for now. Like the beloved Siri on iOS, Indigo is a voice enabled personal assistant that actually chats back at you. It'll look up directions, let you leave notes and reminders, find restaurants and showtimes, and most importantly, play YouTube videos, let you update Facebook, and also read, tweet, and retweet on Twitter. As with any app this advanced, there are plenty of kinks to work out and bugs to squash, but just because this isn't quite Cortana from the Halo games series doesn't mean it isn't really cool!

The Traveler from Frog Baby Apps is looking to be the ultimate app for documenting any and every vacation you ever take, from family road trips to nowhere USA to gallivanting tours across Europe and the rest. The app will let you record video and take photos, sketch things you see and leave notes, and even record your paths, replaying them and showing any photos, videos, or sketches you take at the context appropriate times. Talk about a literal walk down memory lane. This is a great concept and should definitely be downloaded by anyone who travels with regularity.

People have had to figure out all new ways to date and find that significant other in the Internet age, and 'Swoon: who's crushing on you?' is just the latest in a long line of OKCupids and lesser OKCupids. Breaking things down to a basic level of face shots and primary interests, you can play a little game of 'hot or not' and like or pass on various people in your given area anonymously, and you can even message each other in-app if it turns out that you and someone else 'like' each other's profiles. The app is super buggy at the moment, but it's a neat idea worth checking out if online dating is your scene.

SendHub from InfoReach is the latest in a long line of apps that seek to make business communications easier, while also keeping your personal number as personal as possible. Offering a voice over internet alternative phone service, you can make a free business line in any area code, text and call right from the app, plus enjoy nifty features like call forwarding, group texting, voicemail, and the rest. It's also got a few bugs skittering about in its system, but it works quite well as is, and is definitely a great place to look if you want to keep your business and personal lives separate.


Best Educational Apps, Handpicked By Experts

Appolicious is pleased to introduce appoLearning.com, where parents, teachers and students find great education apps. Check out our introduction video here!


Source: http://www.androidapps.com/tech/articles/13432-one-today-by-google-leads-android-apps-of-the-week

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Thursday, April 25, 2013

ARM reports 28% rise in Q1 revenue - Computer Business Review

CBR Staff Writer Published 24 April 2013

Driven by the increasing demand for microchip designs

UK based semiconductor and software design company ARM Holdings has reported 28% increase in revenue for the first quarter of 2013 to ?170.3m from ?132.5m it reported during the same period prior year.

The company recorded 25% rise in mobile chip shipments while the embedded shipments increased by 50% compared to the same period last year.

In the first quarter of 2013, company's pretax profit grew 44% to ?89.4m from ?61.9m in 2012. .

The adjusted EPS for the quarter increased 58% to 5.31pence from 3.36 pence in the same period last year.

For the quarter, the total IFRS operating expenses of the company were ?95.2m that increased from the ?76.2m recorded during first quarter of 2012.

During the period, the company signed 22 processor licenses in different markets including smartphones, mobile computing, digital television and other technology.

The company has reported 35% increase in shipments of ARM-based chips to 2.6 billion units compared to corresponding period last year.

ARM Holdings chief executive officer Warren East said the company has reported strong revenue and earnings growth, driven by robust licensing and royalty revenue.

"In particular, this quarter ARM saw strong uptake of its next generation, higher royalty bearing ARMv8, Mali and big.LITTLE technology for smartphones and mobile computers," East said.

"ARM's royalty revenues again outpaced the wider semiconductor industry. This outperformance has been driven by market share gains in key end markets including digital TVs and microcontrollers.

"In addition, the growth in smartphones and tablets continues to benefit ARM. Even low cost smart devices can contain multiple ARM-based chips and be based on ARM's advanced Cortex-A series technology and Mali graphics processors."

Source: http://www.cbronline.com/news/arm-reports-28-rise-in-q1-revenue-240413

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Sharon Osbourne 'Devastated' By Ozzy Relapse, Denies Divorce Rumors

'Everybody knows he's been struggling with this his entire life,' Sharon says about Ozzy's drug issues.
By Gil Kaufman

Source: http://www.mtv.com/news/articles/1706231/sharon-ozzy-osbourne-relapse-divorce-rumors.jhtml

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Scientist identifies protein molecule used to maintain adult stem cells in fruit flies

Scientist identifies protein molecule used to maintain adult stem cells in fruit flies

Tuesday, April 23, 2013

Understanding exactly how stem cells form into specific organs and tissues is the holy grail of regenerative medicine. Now a UC Santa Barbara researcher has added to that body of knowledge by determining how stem cells produce different types of "daughter" cells in Drosophila (fruit flies). The findings appear today in the Proceedings of the National Academy of Sciences.

Denise Montell, Duggan Professor of Molecular, Cellular and Developmental Biology at UCSB, and colleagues studied the ovaries of fruit flies in order to see stem cells in their natural environment. Because these organisms are excellent models for understanding stem cell biology, researchers were able to shed light on the earliest stages of follicle cell differentiation, a previously poorly understood area of developmental biology. "It is clear that the fundamental principles that control cell behavior in simple animals are conserved and control the behavior of our cells as well," she said. "There is so much we can learn by studying simple organisms."

Using a nuclear protein expressed in follicle stem cells (FSCs), the researchers found that castor, which plays an important role in specifying which types of brain cells are produced during embryonic development, also helps maintain FSCs throughout the life of the animal. "Having identified this important protein molecule in fruit flies, we can test whether the human version of the protein is important for stem cells and their daughters as well," said Montell. "The more we know about the molecules that govern stem cell behavior, the closer we will get to controlling these cells."

Her research team placed the evolutionarily conserved castor (Cas) gene, which encodes a zinc finger protein, in a genetic circuit with two other evolutionarily conserved genes, hedgehog (Hh) and eyes absent (Eya), to determine the fates of specific cell progeny (daughters). What's more, they identified Cas as a critical, tissue-specific target of Hh signaling, which not only plays a key role in maintaining follicle stem cells but also assists in the diversification of their progeny.

The study also shows that complementary patterns of Cas and Eya reveal the gradual differentiation of polar and stalk precursor cells at the earliest stages of their development. In addition, it provides a marker for cell fates and insight into the molecular and cellular mechanisms by which FSC progeny diverge into distinct fates.

Follicle cells undergo a binary choice during early differentiation. Those that turn into specialized cells found at the poles of egg chambers go on to make two cell types: polar and stalk. The three genes, Cas, Eya and Hh, work in various combinations, sometimes repressively, to determine which types of cells are formed. Cas is required for polar and stalk cell fate specification, while Eya is a negative regulator of these cells' fate. Hh is necessary for Cas to be expressed, and Hh signaling is essential to repress Eya.

"If you just had one of these markers, it was hard to tell what's going on," explained Montell. "All the cells looked the same and you had no idea when or how the process occurred. But now we can actually see how the cells acquire different identities."

Hh also plays many roles in embryonic development, adult homeostasis, birth defects, and cancer. Hh antagonists are currently in clinical trials for the treatment of several types of cancer. However, Hh signaling is important in so many different cell types and tissues that systemic delivery of such inhibitors may cause serious side effects. Therefore identifying the essential, tissue-specific effectors of Hh has the potential to lead to the identification of more specific therapeutic targets.

Someday, targeted inhibition of Hh signaling may be effective in the treatment and prevention of many types of human cancers.

###

University of California - Santa Barbara: http://www.ucsb.edu

Thanks to University of California - Santa Barbara for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 22 time(s).

Source: http://www.labspaces.net/127866/Scientist_identifies_protein_molecule_used_to_maintain_adult_stem_cells_in_fruit_flies

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KALQ Is A New Split-Screen Keyboard Layout Designed To Speed Up Thumb Typing On Tablets & Big Phones

KALQ keyboard by University of St AndrewsNew keyboard layout KALQ is designed to speed up thumb typing on tablets and phablets. Its creators, from the University of St Andrews, the Max Planck Institute for Informatics and Montana Tech, claim that once users have accustomed themselves to the unfamiliar non-Qwerty layout typing performance can become about a third (34%) more efficient than thumb typing on split screen Qwerty layouts.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/71VCYOxxzzg/

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Wednesday, April 24, 2013

Scientist identifies protein molecule used to maintain adult stem cells in fruit flies

Scientist identifies protein molecule used to maintain adult stem cells in fruit flies

Tuesday, April 23, 2013

Understanding exactly how stem cells form into specific organs and tissues is the holy grail of regenerative medicine. Now a UC Santa Barbara researcher has added to that body of knowledge by determining how stem cells produce different types of "daughter" cells in Drosophila (fruit flies). The findings appear today in the Proceedings of the National Academy of Sciences.

Denise Montell, Duggan Professor of Molecular, Cellular and Developmental Biology at UCSB, and colleagues studied the ovaries of fruit flies in order to see stem cells in their natural environment. Because these organisms are excellent models for understanding stem cell biology, researchers were able to shed light on the earliest stages of follicle cell differentiation, a previously poorly understood area of developmental biology. "It is clear that the fundamental principles that control cell behavior in simple animals are conserved and control the behavior of our cells as well," she said. "There is so much we can learn by studying simple organisms."

Using a nuclear protein expressed in follicle stem cells (FSCs), the researchers found that castor, which plays an important role in specifying which types of brain cells are produced during embryonic development, also helps maintain FSCs throughout the life of the animal. "Having identified this important protein molecule in fruit flies, we can test whether the human version of the protein is important for stem cells and their daughters as well," said Montell. "The more we know about the molecules that govern stem cell behavior, the closer we will get to controlling these cells."

Her research team placed the evolutionarily conserved castor (Cas) gene, which encodes a zinc finger protein, in a genetic circuit with two other evolutionarily conserved genes, hedgehog (Hh) and eyes absent (Eya), to determine the fates of specific cell progeny (daughters). What's more, they identified Cas as a critical, tissue-specific target of Hh signaling, which not only plays a key role in maintaining follicle stem cells but also assists in the diversification of their progeny.

The study also shows that complementary patterns of Cas and Eya reveal the gradual differentiation of polar and stalk precursor cells at the earliest stages of their development. In addition, it provides a marker for cell fates and insight into the molecular and cellular mechanisms by which FSC progeny diverge into distinct fates.

Follicle cells undergo a binary choice during early differentiation. Those that turn into specialized cells found at the poles of egg chambers go on to make two cell types: polar and stalk. The three genes, Cas, Eya and Hh, work in various combinations, sometimes repressively, to determine which types of cells are formed. Cas is required for polar and stalk cell fate specification, while Eya is a negative regulator of these cells' fate. Hh is necessary for Cas to be expressed, and Hh signaling is essential to repress Eya.

"If you just had one of these markers, it was hard to tell what's going on," explained Montell. "All the cells looked the same and you had no idea when or how the process occurred. But now we can actually see how the cells acquire different identities."

Hh also plays many roles in embryonic development, adult homeostasis, birth defects, and cancer. Hh antagonists are currently in clinical trials for the treatment of several types of cancer. However, Hh signaling is important in so many different cell types and tissues that systemic delivery of such inhibitors may cause serious side effects. Therefore identifying the essential, tissue-specific effectors of Hh has the potential to lead to the identification of more specific therapeutic targets.

Someday, targeted inhibition of Hh signaling may be effective in the treatment and prevention of many types of human cancers.

###

University of California - Santa Barbara: http://www.ucsb.edu

Thanks to University of California - Santa Barbara for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 54 time(s).

Source: http://www.labspaces.net/127866/Scientist_identifies_protein_molecule_used_to_maintain_adult_stem_cells_in_fruit_flies

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UK says "no clear reason" to let independent Scotland use sterling

By David Milliken

LONDON (Reuters) - The euro zone's experience of countries sharing a currency but not a government shows there is no clear case for an independent Scotland to use sterling, Britain's finance ministry said on Tuesday.

The nation of 5 million will hold a referendum on September 18 next year to decide whether to split from the United Kingdom, at the instigation of the Scottish National Party that runs the country's devolved government.

Pro-independence campaigners want Scotland to keep sterling, at least in the early years of independence, and then to decide later whether to switch to its own currency.

But in a report on Tuesday, Britain's finance ministry said there was no clear case for the United Kingdom to agree to a formal currency union with an independent Scotland, which would have an economy of a similar size to New Zealand's.

"The economic rationale for the UK to agree to enter a formal sterling union with a separate state is not clear," said the report, which was prepared by non-partisan civil servants.

"The recent experience of the euro area has shown that it is extremely challenging to sustain a successful formal currency union without close fiscal integration and common arrangements for the resolution of banking sector difficulties," it added.

Conservative finance minister George Osborne and his Liberal Democrat deputy Danny Alexander, who insist Scotland would be better off remaining part of the United Kingdom, are due to present the report in Glasgow later on Tuesday.

Financial markets are unperturbed by what they see as a remote prospect of Scottish independence, but there could be major implications for sterling and the British government bond market if this perception changed.

Markets could easily force a currency union to break up after independence if they did not think there was a solid commitment to it on both sides, imposing costs on both Scotland and the rest of Britain, the report said.

Moreover, there would be complex issues to be decided on whether the Bank of England could continue to be a lender of last resort to Scottish banks, and Britain would want "rigorous oversight" of an independent Scotland's fiscal policies.

The report reached a similar conclusion and highlighted further risks for Scotland if it decided to use sterling unilaterally, join the euro or create its own currency.

Scotland's economy was heavily exposed to the volatile oil and gas sector, and more similar to the economy in the rest of Britain than to that of the euro zone, the report said.

"The current currency and monetary policy arrangements within the UK serve Scotland well," the report said. But after independence, "the status quo would not be one of the options".

"All of the alternative currency arrangements would be likely to be less economically suitable for both Scotland and the rest of the UK."

The report is part of a series by the British government that it hopes will inform the referendum debate.

Opinion polls show around 30 percent of Scots are currently in favor of independence, while 50 percent are against.

(Editing by Alison Williams)

Source: http://news.yahoo.com/uk-says-no-clear-reason-let-independent-scotland-230532493--business.html

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White House refuses to say if Obama still supports disclosing library donors (Washington Bureau)

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Tuesday, April 23, 2013

CamFind Is a More Accurate Google Goggles

iOS: Google Googles is a great way to search for objects in the real world based on an image, but it's not exactly the most accurate app out there. CamFind does the same basic trick, but it's a little more accurate and provides a wealth of information.

Like Google Goggles, you just need to snap a picture of something in CamFind, and it hunts down the image to give you information. This can be text, landmarks, products, books, art, translations, and even movie posters. Once you snap a picture, CamFind searches for similar images and then provides you with shopping information, related places, Yelp results, and more. Compared side-by-side, CamFind seems a bit more accurate then Google Goggles, albeit a little slower on the search itself. If you tried out Google Goggles and were underwhelmed by the results, CamFind's worth a look.

CamFind (Free) | iTunes App Store

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/t0zTLVAWAQ4/camfind-is-a-more-accurate-google-goggles-476849886

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Earth's current warmth not seen in the last 1,400 years or more, says study

Apr. 21, 2013 ? Fueled by industrial greenhouse gas emissions, Earth's climate warmed more between 1971 and 2000 than during any other three-decade interval in the last 1,400 years, according to new regional temperature reconstructions covering all seven continents. This period of humanmade global warming, which continues today, reversed a natural cooling trend that lasted several hundred years, according to results published in the journal Nature Geoscience by more than 80 scientists from 24 nations analyzing climate data from tree rings, pollen, cave formations, ice cores, lake and ocean sediments, and historical records from around the world.

"This paper tells us what we already knew, except in a better, more comprehensive fashion," said study co-author Edward Cook, a tree-ring scientist at Lamont-Doherty Earth Observatory who led the Asia reconstruction.

The study also found that Europe's 2003 heat wave and drought, which killed an estimated 70,000 people, happened during Europe's hottest summer of the last 2,000 years. "Summer temperatures were intense that year and accompanied by a lack of rain and very dry soil conditions over much of Europe," said study co-author Jason Smerdon, a climate scientist at Lamont-Doherty and one of the lead contributors to the Europe reconstruction. Though summer 2003 set a record for Europe, global warming was only one of the factors that contributed to the temperature conditions that summer, he said.

The study is the latest to show that the Medieval Warm Period, from about 950 to 1250, may not have been global, and may not have happened at the same time in places that did grow warmer. While parts of Europe and North America were fairly warm between 950 and 1250, South America stayed relatively cold, the study says. Some people have argued that the natural warming that occurred during the medieval ages is happening today, and that humans are not responsible for modern day global warming. Scientists are nearly unanimous in their disagreement "If we went into another Medieval Warm Period again that extra warmth would be added on top of warming from greenhouse gases," said Cook.

Temperatures varied less between continents in the same hemisphere than between hemispheres. "Distinctive periods, such as the Medieval Warm Period or the Little Ice Age stand out, but do not show a globally uniform pattern," said co-author Heinz Wanner, a scientist at the University of Bern. By 1500, temperatures dropped below the long-term average everywhere, though colder temperatures emerged several decades earlier in the Arctic, Europe and Asia.

The most consistent trend across all regions in the last 2,000 years was a long-term cooling, likely caused by a rise in volcanic activity, decrease in solar irradiance, changes in land-surface vegetation, and slow variations in Earth's orbit. With the exception of Antarctica, cooling tapered off at the end of the 19th century, with the onset of industrialization. Cooler 30-year periods between 830 and 1910 were particularly pronounced during weak solar activity and strong tropical volcanic eruptions. Both phenomena often occurred simultaneously and led to a drop in the average temperature during five distinct 30- to 90-year intervals between 1251 and 1820. Warming in the 20th century was on average twice as large in the northern continents as it was in the Southern Hemisphere. During the past 2000 years, some regions experienced warmer 30-year intervals than during the late 20th century. For example, in Europe the years between 21 and 80 AD were likely warmer than the period 1971-2000.

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The above story is reprinted from materials provided by The Earth Institute at Columbia University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Moinuddin Ahmed, Kevin J. Anchukaitis, Asfawossen Asrat, Hemant P. Borgaonkar, Martina Braida, Brendan M. Buckley, Ulf B?ntgen, Brian M. Chase, Duncan A. Christie, Edward R. Cook, Mark A. J. Curran, Henry F. Diaz, Jan Esper, Ze-Xin Fan, Narayan P. Gaire, Quansheng Ge, Jo?lle Gergis, J Fidel Gonz?lez-Rouco, Hugues Goosse, Stefan W. Grab, Nicholas Graham, Rochelle Graham, Martin Grosjean, Sami T. Hanhij?rvi, Darrell S. Kaufman, Thorsten Kiefer, Katsuhiko Kimura, Atte A. Korhola, Paul J. Krusic, Antonio Lara, Anne-Marie L?zine, Fredrik C. Ljungqvist, Andrew M. Lorrey, J?rg Luterbacher, Val?rie Masson-Delmotte, Danny McCarroll, Joseph R. McConnell, Nicholas P. McKay, Mariano S. Morales, Andrew D. Moy, Robert Mulvaney, Ignacio A. Mundo, Takeshi Nakatsuka, David J. Nash, Raphael Neukom, Sharon E. Nicholson, Hans Oerter, Jonathan G. Palmer, Steven J. Phipps, Maria R. Prieto, Andres Rivera, Masaki Sano, Mirko Severi, Timothy M. Shanahan, Xuemei Shao, Feng Shi, Michael Sigl, Jason E. Smerdon, Olga N. Solomina, Eric J. Steig, Barbara Stenni, Meloth Thamban, Valerie Trouet, Chris S.M. Turney, Mohammed Umer, Tas van Ommen, Dirk Verschuren, Andre E. Viau, Ricardo Villalba, Bo M. Vinther, Lucien von Gunten, Sebastian Wagner, Eugene R. Wahl, Heinz Wanner, Johannes P. Werner, James W.C. White, Koh Yasue, Eduardo Zorita. Continental-scale temperature variability during the past two millennia. Nature Geoscience, 2013; DOI: 10.1038/ngeo1797

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/nvWQkE89Z-A/130422101313.htm

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An Evidence-Based Approach to Managing Chemotherapy-Induced ...

Presented by: Carrie Stricker, PhD, RN, AOCN
The Abramson Cancer Center of the University of Pennsylvania
Last Modified: April 22, 2013

This continuing education activity is designed for nurses and nurse practitioners in clinical practice to learn about the assessment, prevention and control of chemotherapy-induced nausea and vomiting (CINV). This activity has been approved for 1.0 contact hour by the Hospital of the University of Pennsylvania, Department of Nursing Development and Education, an approved provider of continuing nursing education by the PA State Nurses Association, an accredited approver by the American Nurses Credentialing Center's Commission on Accreditation.

To receive continuing education credits for this activity:

  • Watch the video presentation by Dr. Stricker, which will open in a new window.
  • Return to this page, click on the link to go to the posttest, fill in your contact information and complete the test.
  • If you do not achieve a passing score, you will return to the test and be able to retake the posttest.
  • If you achieve a score of 80% or higher, you can proceed to the evaluation form.
  • Once you submit the evaluation, the CE certificate will pop up. Please print this for your records.

The educational objectives of this activity are:

  • To describe the underlying mechanisms of chemotherapy induced nausea and vomiting (CINV).
  • To discuss contemporary evidence for best practice in prevention and control of CINV.
  • To overview strategies for translating CINV evidence into clinical practice, including via development and implementation of institutional guidelines.

PROCEED TO VIDEO PRESENTATION

An Evidence-Based Approach to Managing Chemotherapy-Induced Nausea and Vomiting - Continuing Education Post-Test

Source: http://www.oncolink.org/resources/article.cfm?c=412&id=1097

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Flashback! See Kris & Bruce Jenner?s Wedding Photo

The happy couple celebrates 22 years of marriage! Check out other cute and candid moments from the stars

Source: http://www.ivillage.com/celebrity-twitter-pictures/1-b-229669?dst=iv%3AiVillage%3Acelebrity-twitter-pictures-229669

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Thursday, April 18, 2013

When religion overrides parental duty - West

?You?re gay? Then we?re giving you up for adoption.? A married couple from South Carolina have caused public outrage in the US when they announced they would be giving their teenage daughter up for adoption ? just because of her sexual orientation.

The news sounds far-fetched. Abandoning one?s child for economic reasons is common, when the means to raise a human being in dignity are lacking, or for psychological reasons if the parent doesn?t feel ready to support and guide a child. However, this is the first noted case in which a parent gives a child up for adoption because the child is homosexual.

The case is even more striking because the child in question is not a baby, but a 16-year-old adolescent. To be abandoned at an age when you are fully aware of circumstances must be worse than being given up for adoption as a baby. However, the state of South Carolina has declared that the girl is legally adoptable and she is currently a ward of the state.

The girl, April Chadwell, must have thought deeply before announcing her sexuality to her family and, particularly because of her young age, she may have been anxious about doing so. But when it came to telling her parents, perhaps hoping for understanding and support from them, instead she was met with an unimaginable response.

Mrs. Chadwell explained to the press that the choice had been painful for her and her husband but that they were not able to deal with a situation they didn?t agree with ? and which they found incomprehensible and intolerable. They therefore turned to their local church, which they attended faithfully, and preferred to pray for April, who would be better off living with a family that knows how to treat her with love and tolerance.

Is it ever too late to take a step backwards, because of one?s own limitations and the awareness that one?s own behaviour might be more harmful to a child than giving that child up? Or, on the other hand, might the child suffer more, being aware that he or she is alone in the world just because their parents had strong views that their parental feelings were not able to overcome?

Source: http://www.west-info.eu/when-religion-overrides-parental-duty/

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Scientists discover new materials to capture methane

Wednesday, April 17, 2013

Scientists at Lawrence Livermore National Laboratory (LLNL) and UC Berkeley and have discovered new materials to capture methane, the second highest concentration greenhouse gas emitted into the atmosphere.

Methane is a substantial driver of global climate change, contributing 30 percent of current net climate warming. Concern over methane is mounting, due to leaks associated with rapidly expanding unconventional oil and gas extraction, and the potential for large-scale release of methane from the Arctic as ice cover continues to melt and decayed material releases methane to the atmosphere. At the same time, methane is a growing source of energy, and aggressive methane mitigation is key to avoiding dangerous levels of global warming.

The research team, made up of Amitesh Maiti, Roger Aines and Josh Stolaroff of LLNL and Berend Smit at UC Berkeley and Lawrence Berkeley National Lab, performed systematic computer simulation studies on the effectiveness of methane capture using two different materials ? liquid solvents and nanoporous zeolites (porous materials commonly used as commercial adsorbents).

While the liquid solvents were not effective for methane capture, a handful of zeolites had sufficient methane sorption to be technologically promising. The research appears in the April 16 edition of the journal, Nature Communications.

Unlike carbon dioxide, the largest emitted greenhouse gas, which can be captured both physically and chemically in a variety of solvents and porous solids, methane is completely non-polar and interacts very weekly with most materials.

"Methane capture poses a challenge that can only be addressed through extensive material screening and ingenious molecular-level designs," Maiti said.

Methane is far more potent as a greenhouse gas than CO2. Researchers have found that the release of as little as 1 percent of methane from the Arctic alone could have a warming effect approaching that being produced by all of the CO2 that has been pumped into the atmosphere by human activity since the start of the Industrial Revolution.

Methane is emitted at a wide range of concentrations from a variety of sources, including natural gas systems, livestock, landfills, coal mining, manure management, wastewater treatment, rice cultivation and a few combustion processes.

The team's research focused on two different applications -- concentrating a medium-purity methane stream to a high-purity range (greater than 90 percent), as involved in purifying a low-quality natural gas; and concentrating a dilute stream (about 1 percent or lower) to the medium-purity range (greater than 5 percent), above methane's flammability limit in air.

Through an extensive study, the team found that none of the common solvents (including ionic liquids) appears to possess enough affinity toward methane to be of practical use. However, a systematic screening of around 100,000 zeolite structures uncovered a few nanoporous candidates that appear technologically promising.

Zeolites are unique structures that can be used for many different types of gas separations and storage applications because of their diverse topology from various networks of the framework atoms. In the team's simulations, one specific zeolite, dubbed SBN, captured enough medium source methane to turn it to high purity methane, which in turn could be used to generate efficient electricity.

"We used free-energy profiling and geometric analysis in these candidate zeolites to understand how the distribution and connectivity of pore structures and binding sites can lead to enhanced sorption of methane while being competitive with CO2 sorption at the same time," Maiti said.

Other zeolites, named ZON and FER, were able to concentrate dilute methane streams into moderate concentrations that could be used to treat coal-mine ventilation air.

###

DOE/Lawrence Livermore National Laboratory: http://www.llnl.gov

Thanks to DOE/Lawrence Livermore National Laboratory for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 14 time(s).

Source: http://www.labspaces.net/127782/Scientists_discover_new_materials_to_capture_methane

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Wednesday, April 17, 2013

Quake kills at least 46 along Iran-Pakistan border

TEHRAN, Iran (AP) ? A major earthquake described as the strongest to hit Iran in more than half a century flattened homes and offices Tuesday on both sides of the Iran-Pakistan border, killing at least 46 people in the sparsely populated region and swaying skyscrapers and buildings as far away as New Delhi.

Iran's Red Crescent said it was facing a "complicated emergency situation" in the area with villages scattered over desolate hills and valleys.

Iran's semiofficial ISNA news agency and others described the quake, measured at least magnitude 7.7, as the strongest quake in more than 50 years. State-run Press TV called it a "massive quake."

It also was the second deadly quake to hit Iran in less than a week after a magnitude 6.1 temblor struck near Bushehr, on Iran's Persian Gulf coast, killing at least 37 people and raising calls for greater international safety inspectors at Iran's lone nuclear reactor nearby.

Press TV said the quake was centered near Saravan, about 50 kilometers (26 miles) from the Pakistani border. A previous report citing the country's seismological center placed the strength at magnitude 7.5, but it was apparently revised upward. The U.S. Geological Survey put the preliminary magnitude at 7.8 and at a depth of 15.2 kilometers (nine miles).

Press TV said least 40 people were killed, but gave no other immediate details on the extent of damage or casualties. State-run Pakistan Television, meanwhile, said at least six people were killed on its side of the border and at least 47 others were injured. Up to 1,000 mud homes were damaged, it added.

The quake was felt over a vast area from New Delhi to Gulf cities that have some of the world's tallest skyscrapers, including the record 828-meter (2,717 -foot) Burj Khalifa in Dubai. Officials ordered temporary evacuations from some high-rises as a precaution.

A resident in the quake zone, Manouchehr Karimi, told The Associated Press by phone that "the quake period was long" and occurred "when many people were at home to take a midday nap."

Pakistani news channels showed buildings shaking in the southern city of Karachi, where people in panic came out from offices and homes.

In a message posted on Twitter, British Foreign Secretary William Hague sent condolences to families of those lost in the Iran earthquake.

In 2003, some 26,000 people were killed by a magnitude 6.6 quake that flattened the historic southeastern Iranian city of Bam.

___

Associated Press writer Abdul Sattar in Quetta, Pakistan, contributed to this story.

Source: http://news.yahoo.com/quake-kills-least-46-along-iran-pakistan-border-132849716.html

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FCC Issues Two Forfeiture Notices for Cell Phone Jamming

04/15/2013

On April 9, the FCC found two businesses -- The Supply Room in Oxford, Alabama and Taylor Oilfield Manufacturing in Broussard, Louisiana -- to have ?apparently willfully and repeatedly violated Sections 301, 302(b), and 333 of the Communications Act of 1934, as amended, and Sections 2.803(g) and 15.1(c) of the Commission?s rules by operating multiple cellular phone jammers.? In addition, the FCC found that both businesses each imported five illegal signal jamming devices in violation of Section 302(b) of the Act and Sections 2.1203 and 2.1204 of the Rules; Section 2 dictates the conditions under which radio frequency devices may be imported into the US. The FCC issued a Notice of Apparent Liability for Forfeiture and Order (NAL) to each business: The Supply Room received an NAL in the amount of $144,000 (FCC No. 13-47), while Taylor Oilfield Manufacturing received an NAL in the amount of $126,000 (FCC No, 13-46).

The FCC received anonymous tips that cell phone jamming was occurring at both businesses. By using direction finding techniques, FCC agents discovered ?strong wideband emissions in the cellular bands? that they determined to be ?one or more signal jammers? at each site. Both The Supply Room and Taylor Oilfield Manufacturing admitted to the agents that they had each purchased five signal jammers off of the Internet from overseas sources.

While The Supply Room?s general manager admitted to the FCC agent that the jammers were in place ?to prevent its employees from using their cellular phones while working? and they had been in operation for more than two years, the manager of Taylor Oilfield Manufacturing told the FCC agent that it ?utilized the jamming devices to prevent its employees from using their cellular phones while working, apparently following a near-miss industrial accident that allegedly was partially attributable to employee cell phone use,? and that the jammers had only been in operation ?for a few months.? Both entities voluntarily surrendered their jammers to the FCC.

?Signal jamming devices operate by transmitting powerful radio signals that overpower, jam or interfere with authorized communications,? the FCC noted. ?While these devices have been marketed with increasing frequency over the Internet, with limited exception, they have no lawful use in the United States. Jammers are not only designed to impede authorized communications and thereby interfere with the rights of legitimate spectrum users and the general public, but also are inherently unsafe. For example, jammers can be used to disrupt critical public safety communications, placing first responders like law enforcement and fire fighting personnel -- as well as the public they are charged with protecting -- at great risk. Similarly, jammers can endanger life and property by preventing individuals from making 9-1-1 or other emergency calls. In order to protect the public and preserve unfettered access to emergency and other communications services, the [Communications] Act generally prohibits the importation, use, marketing, manufacture, and sale of jammers. The Commission has issued several enforcement advisories and consumer alerts emphasizing the importance of strict compliance in this area and encouraging public participation through the Commission?s jammer tip line.?

The FCC directed both The Supply Room and Taylor Oilfield Manufacturing to submit payment in full by May 9, 2013, or file a written statement seeking reduction or cancellation of the proposed forfeiture. Both entities were also directed to file a statement to be signed under penalty of perjury no later than May 9, 2013, that would provide information concerning the source(s) from which each business purchased or received the jamming devices.

?

Source: http://www.arrl.org/news/view/fcc-issues-two-forfeiture-notices-for-cell-phone-jamming

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Tuesday, April 16, 2013

Birds Of A Feather: The Escape Of Sao Paulo

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Asian Markets, April 16, 2013 - Business Insider

Markets have just opened in Asia, and they are trading lower.

Japan's Nikkei is down 1.6%.

Korea's Kospi is down 1.0%.

Australia's S&P/ASX is down 0.4%.

The sell-off comes in the wake of disappointing U.S. economic reports and a sharp Monday stock market plunge.

Gold tumbled by as much as 10% today.

Just before 3:00 PM ET, there were at least two explosions near the finish line of the Boston Marathon.? At least 22 are reportedly injured and 2 dead.? The story is developing.

Source: http://www.businessinsider.com/asian-markets-april-16-2013-2013-4

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